News in Sleep Medicine

Research into Obstructive Sleep Apnea

We will post cutting-edge medical journal research results on this page.  They will be updated as new information comes to light.  The references have been included in case you wish to review the article yourself.  If you have any questions about an article, please click here to send us an email.

January 2014

1)  Upper Airway Stimulation for Obstructive Sleep Apnea

Source:  Strollo Jr., PH, et al.  Upper Airway Stimulation for Obstructive Sleep Apnea.  New England Journal of Medicine 2014; 370:139-149.

Results:  For a specific group of people, putting in a breathing “pacemaker” that helps increase tone in the airway when you stop breathing will help improve sleep apnea indices by up to 70%.  Patients in this study had an average body mass index of 29.  For more information, see inspiresleep.com.

June 2013

1)  Sleep Fragmentation and the Risk of Incident Alzheimer’s Disease and Cognitive Decline in Older Persons

Source: Lim, ASP, et al.  Sleep Fragmentation and the Risk of Incident Alzheimer’s Disease and Cognitive Decline in Older Persons.  Sleep 2013; 36(7):  1027-32.

Results:  Increasing sleep fragmentation in patients older than 65 years of age led to increases in both cognitive decline without dementia, and increases in incident Alzheimer’s disease.

February 2013

1)  Memory and Obstructive Sleep Apnea

Source:  Wallace A; Bucks RS. Memory and obstructive sleep apnea: a meta-analysis. SLEEP 2013;36(2):203-220.

Results:  Compared to normal healthy people, people who suffer from obstructive sleep apnea who are not treated experience significant problems with memory, including immediate and delayed recall, learning and recognition.

January 2013

1)  Treating Sleep-Disordered Breathing In Pregnancy May Improve Fetal Health

Source:  http://www.medicalnewstoday.com/releases/254558.php

Summary:  Treating pregnant women suffering preecclampsia with CPAP therapy improves fetal wellbeing and movements.

September 2012

1)  All-Cause Mortality and Obstructive Sleep Apnea Severity Revisited

Source:  Rich, J, et al. Otolaryngology Head and Neck Surgery, Volume 147, Number 3 (pages 583-587)

Results:  Increasing OSA severity was found to be significantly associated with increased all-cause mortality in patients younger than age 50 years, after adjustment for other major factors.

July 2012

1)  Sleep-Disordered Breathing and Cancer Mortality (Results from the Wisconsin Sleep Cohort Study)

Source:  Nieto, FJ, et al.  American Journal Respiratory Critical Care Medicine.  Volume 186, Number 2 (pages 190-194)

Results: Baseline sleep disordered breathing is associated with increased cancer mortality in a community sample.  The risk increases with increasing severity of obstructive sleep apnea.

May 2012

1)  Effects of Positive Airway Pressure Therapy on Neurobehavioural Outcomes in Children with Obstructive Sleep Apnea

Source:  Marcus, CL, et al.  American Journal Respiratory Critical Care Medicine.  Volume 185, Number 9 (pages 998-1003)

Results:  Even with suboptimal adherence of CPAP therapy, there was a significant improvement in behavioural function in children after three months of CPAP therapy, even in developmentally delayed children.  This included improvements in attention deficits, sleepiness, behaviour and caregiver quality of life.

 
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